The National Precursor Log Exchange (NPLEx) is a real-time electronic logging system used by pharmacies and law enforcement to track sales of over-the-counter (OTC) cold and allergy medications containing precursors to the illegal drug, methamphetamine.

Frequently Asked Questions


How do I get access to NPLEx?

Click here to visit our "access" page. Please be aware that only pharmacies and law enforcement have access to NPLEx. During the application process for access to the system, you will be asked to provide verification of either pharmacy or law enforcement status.


What is NPLEx?

NPLEx is a unique public/private partnership offering a real-time electronic methamphetamine precursor tracking service, free of charge, to law enforcement and state governments.


Who are the partners in the NPLEx system?

The National Association of Drug Diversion Investigators (NADDI) is the provider of the service. The manufacturers of the medicines are the sponsors of NPLEx, and pay for the entire cost of the service. Appriss®, Inc., is the technology vendor whose product, MethCheck, won the competitive bid to provide the service.


What is the cost to state government?

NPLEx is provided free of charge on a permanent basis to state governments that pass appropriate legislation and regulations. This includes implementation to all retailers, access to law enforcement, full 24/7 technical support, training for retailers and law enforcement, and maintenance and upgrades.


How does law enforcement get access to the data in NPLEx?

Law enforcement officers simply visit http://www.nplexle.appriss.com/. Officers self-register by providing a user name, password, and other agency information. Upon verification, the officers will receive an email letting them know their registration request has been approved, and they can begin using the system.


How does NPLEx work?

The federal Combat Methamphetamine Epidemic Act of 2005 (CMEA,) as well as numerous state and local laws, require retailers of products containing pseudoephedrine and ephedrine to capture customer data at the point of sale. The pharmacy scans a government identification or enters the data into the secure MethCheck portal. The information is transmitted instantly to the database where it is available for review by law enforcement.


Why is real-time so important?

Real-time enables the blocking of sales that would exceed the legal limits, thereby potentially preventing the manufacture of methamphetamine. Real-time also prevents customers from inadvertently purchasing too much of the medicine, and finally, real-time gives law enforcement immediate information.


What about servers, software, or hardware?

The NPLEx tool, MethCheck, is entirely web-based, with no servers, software, or hardware. Law enforcement and retailers need only a computer with Internet access.


What is a blocked sale?

All retailers in the system voluntarily block the sale of precursors that would exceed any law of jurisdiction, including 3.6 grams per day and 9 grams in 30 days according to federal law. When a transaction is submitted by a retailer that would exceed the limits, a message is instantly sent to the retailer recommending denial of the sale. A manual override can be used if the clerk feels in danger, and law enforcement is notified that the sale may have exceeded the limits.


pyramidIcon NPLEx Helps Law Enforcement

Do you have a question about NPLEx? Please submit it to us and we'll do our best to answer it. We may even post it in this frequently asked questions section so that others can see.